diff --git a/release/.buildkite/build_pipeline.py b/release/.buildkite/build_pipeline.py
index 93a4b389c..8712f731f 100644
--- a/release/.buildkite/build_pipeline.py
+++ b/release/.buildkite/build_pipeline.py
@@ -132,6 +132,7 @@ CORE_DAILY_TESTS = {
         "dask_on_ray_large_scale_test_spilling",
         "pg_autoscaling_regression_test",
         "threaded_actors_stress_test",
+        "k8s_threaded_actors_stress_test",
         "stress_test_many_tasks",
         "stress_test_dead_actors",
         "many_nodes_actor_test",
diff --git a/release/nightly_tests/nightly_tests.yaml b/release/nightly_tests/nightly_tests.yaml
index 19e7c5b88..4e994ad00 100644
--- a/release/nightly_tests/nightly_tests.yaml
+++ b/release/nightly_tests/nightly_tests.yaml
@@ -295,6 +295,24 @@
       script: python stress_tests/test_threaded_actors.py --test-runtime 1800 --kill-interval_s 30
   stable: false
 
+- name: k8s_threaded_actors_stress_test
+  team: core
+  cluster:
+    app_config: stress_tests/stress_tests_app_config.yaml
+    compute_template: stress_tests/k8s_stress_test_threaded_actor_compute.yaml
+    compute_on_k8s: True
+
+  run:
+    timeout: 7200
+    prepare: python wait_cluster.py 201 600
+    script: python stress_tests/test_threaded_actors.py --test-runtime 3600 --kill-interval_s 60
+
+    run:
+      timeout: 3600
+      prepare: python wait_cluster.py 5 600
+      script: python stress_tests/test_threaded_actors.py --test-runtime 1800 --kill-interval_s 30
+  stable: false
+
 # Test decision tree on autoscaling compute cluster.
 - name: decision_tree_autoscaling
   team: core
diff --git a/release/nightly_tests/stress_tests/k8s_stress_test_threaded_actor_compute.yaml b/release/nightly_tests/stress_tests/k8s_stress_test_threaded_actor_compute.yaml
new file mode 100644
index 000000000..5eab17027
--- /dev/null
+++ b/release/nightly_tests/stress_tests/k8s_stress_test_threaded_actor_compute.yaml
@@ -0,0 +1,26 @@
+cloud_id: cld_HSrCZdMCYDe1NmMCJhYRgQ4p
+region: us-west-2
+
+head_node_type:
+    name: head_node
+    instance_type: m5.8xlarge
+    resources:
+      cpu: 0
+
+worker_node_types:
+   - name: worker_node
+     instance_type: m5.4xlarge
+     min_workers: 200
+     max_workers: 200
+     use_spot: false
+     resources:
+      cpu: 32
+
+aws:
+  TagSpecifications:
+    - ResourceType: "instance"
+      Tags:
+        - Key: anyscale-user
+          Value: '{{env["ANYSCALE_USER"]}}'
+        - Key: anyscale-expiration
+          Value: '{{env["EXPIRATION_1D"]}}'